Due to changes from Microsoft in the Server 2016 and 2019 architectures, Windows Defender Antivirus will not disable itself when other antivirus products are detected. Microsoft has also removed API's for other Antivirus software to cleanly stop and disable Windows Defender AV. This was a design choice by Microsoft to maximize protection in Server 2016 and 2019. 

Because of these changes, Windows Defender Antivirus will still be active and running after VIPRE has installed. This requires manual action because running multiple sets of real-time Antivirus software can lead to performance issues and system instability.  

We recommend disabling Windows Defender at the same time that VIPRE is installed. This can be achieved by executing the following PowerShell command with Administrative rights:

  • Uninstall-WindowsFeature -Name Windows-Defender

This article provides more information on the changes to Windows Defender Security Center in Server 2016: Windows Defender Antivirus for Windows Server

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